Title: Ultrasound-guided fine-needle aspiration biopsy in the management of thyroid disease
Author(s ) ROSEN I. B. (1) ; ABBAS AZADIAN (1) ; WALFISH P. G. ; SHIA SALEM; LANSDOWN E. ; BEDARD Y. C
Author(s) Affiliation(s) (1) Univ. Toronto, Mount Sinai hosp., dep. surgery, Toronto ON, CANADA
Abstract
During a 23-month period, 59 patients were referred for ultrasound (US)-guided tine-needle aspiration biopsy (FNAB) of the thyroid gland because of inadequate orthodox (office) FNAB, a clinically small lesion, or an occult lesion. Seventy percent of the group (41 patients) was referred for surgery, which revealed cancer in 37% of patients, adenoma in 19%, and benign disease in 44%. US-guided FNAB yielded fase-positive reports in 0% of patients, false-negative reports in 5% to 12%, and inadequate aspirates in 32%. The US-guided FNAB technique had a sensitivity of 60% to 90%, a specificity of 100%, a positive predictive value of 100%, a negative predictive value of 80%, and an accuracy of 85%
Journal Title
The American journal of surgery ISSN 0002-9610 CODEN AJSUAB
Abstract
During a 23-month period, 59 patients were referred for ultrasound (US)-guided tine-needle aspiration biopsy (FNAB) of the thyroid gland because of inadequate orthodox (office) FNAB, a clinically small lesion, or an occult lesion. Seventy percent of the group (41 patients) was referred for surgery, which revealed cancer in 37% of patients, adenoma in 19%, and benign disease in 44%. US-guided FNAB yielded fase-positive reports in 0% of patients, false-negative reports in 5% to 12%, and inadequate aspirates in 32%. The US-guided FNAB technique had a sensitivity of 60% to 90%, a specificity of 100%, a positive predictive value of 100%, a negative predictive value of 80%, and an accuracy of 85%
Journal Title
The American journal of surgery ISSN 0002-9610 CODEN AJSUAB
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